The contents of the manuscript are as follows:
(i) `Liber febrium` by Isaac (Isḥāq ibn Sulaiman al-Isrā’ili), translated by Constantinus Africanus, in prologue and five books. The author and translator are given in the contents list only (folio 1).
(ii) `Secretum secretorum` by Pseudo-Aristotle, the medical section translated by Joannes Hispalensis, without title (folio 82). See ‘Speculum’, volume xxxiv, page 24.
(iii) `Micro-tegni’ by Galen, translated by Constantinus Africanus, entitled only `Tegni` (folio 85).
(iv) `De differentia animae et spiritus` by Costa ben Luca (Qustā ben Lūqā), translated by Joannes Hispalensis, without title (folio 104 verso).
(v) `De taxone` by Sextus Placitus (B text; ‘Corpus medicorum latinorum’, volume iv, pages 230-232), without title (folio 108 verso).
(vi) `Liber simplicis medicine`, incipit `Simplex medicina est aut de existentibus per se` (folio 109).
Three main hands wrote (i), (iii) and (vi) respectively; one other added (ii) and (iv), another (v). A Durham hand wrote a contents list on folio iii verso, which includes (i) and (vi) only and concludes `Volumen presens continet supra dicta`; this has been completed by a 15th-century hand.
There are marginal notes in several hands. Headings and initials are in red (green initials on folios 126-128); the initials on folios 10 verso-11 recto have not been added; space has been left for larger initials on folios 1, 26 and 59, but these have not been added.