The manuscript is written in a small and precise hand, akin to that of Adv.MS.72.1.10 but strongly seriffed. There may be an Ó Siaghail connection, cf. folio 5 recto. It begins with a large decorated initial; capitals coloured red to folio 2 recto. Two further hands appear in marginalia, one at folios 2 verso and 5 recto, the other elsewhere as listed below; there are also some obscure marks or scrawls (folios 3 recto, 4 recto). The marginalia include three love-charms, all beginning ‘Bran ber’. On Aphorisms of Hippocrates, cf. Adv.MS.72.1.10, folio 1 recto, column a, line 37. Beginning ‘Quecumque in utiro habent hiis concluditur os matricis et cetera .i. iseadh adeir Ipocrait and sea gach bean ga mbi an toircis bid bel in macluic dunta’ (book 5, number 51). Ends incomplete, folio 8 verso: ‘Late postuili non uailde et cetera .i. o do labair Ipocrait asin canoin so tuas dona credaib’ (book 6, number 9). Also covered by Adv.MS.72.2.10, pages 1-56 (abridged version). Authorities cited: Galen, Isaac, Aristotle, G(il)b(ertinus), Gerallterus (folio 6 recto, column a, line 8), Ricardus (6r), Avicenna. (Folio 1 recto, column a, line 1.)

The manuscript contains the following marginalia.

(i) ‘Na assir clach na curri grian ni biadh urri acht an rath riogh’. (Folio 2 verso.)

(ii) “Dé beatha a dheighmic ma ríog”, 1 quatrain; ‘misi me’. (Folio 3 verso.)

(iii) “Mo mhallacht air Dhiarmuid O Shiaghail, is lom do cuir a bhen mo colladh do dhí orum areir”. (Folio 5 recto.)

(iv) “Bran ber breas eo erobi. Cur a slait cháorthainn ⁊ da ndeca pher tairrs ni fuidhther pit aici”. (Folio 5 verso.) (a) ‘amen as maith an litir’. (b) “Fa gráss ní éur eunduine”, 2 lines.(c) ‘Bran ber bera ears earb. Cur a slait chaorthainn ⁊ da ndecha fer thairsi ni eirgheann air’. (Folio 6 recto.)

(v) “Bran ber ar thelar ibe. A cur a slait chuill ⁊ púail tri bhuilli ar mhnaoí dhe. ⁊ carfuidh thú”. (6 verso.)

(vi) ‘Commortus risin ufer do scrioph ……… agam’. (8 verso.)