There are similarities of writing and of material with MS.6504 (compare MS.6504, folio 70 verso with MS.6505, folio 46 inverted). The volume indicates that the owner of the library was a man of wide interests; apart from a well-documented section on medicine (folios 9-16), other subjects, for example, theology (folios 1-6), are well represented.

There are a few eighteenth-century additions.