The letters here are mainly of Henry Richard Vassall Fox (Lord Holland) to John Murray [II], although there are also some of Elizabeth Fox to the same recipient. The letters largely relate to the publication process for works about Walpole and Waldegrave in which Lord Holland was involved, but there are also letters of introduction and mentions of other topics, including the poetry of Lord Byron.

In addition to these letters are typescript transcriptions of other letters of Henry Fox to John Murray [II]. These transcriptions were made in the 20th century.